Charged Dendrimers Revisited: Effective Charge and Surface Potential of Dendritic Polyglycerol Sulfate
نویسندگان
چکیده
منابع مشابه
Effective interactions between charged dendrimers
We perform monomer-resolved computer simulations of fourth-generation charged dendrimers at various conditions of charging (full, terminal and neutral) and for different values of the spacer length P connecting the branching nodes, fromP1⁄4 1 toP1⁄4 6.We examine the sizes, overlaps and effective forces between the centers ofmass of the dendrimers with andwithout addedmonovalent and divalent sal...
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PAMAM dendrimers are used as a model system to investigate the effects of counterion condensation and the effective charge for spherical polyelectrolytes. Because of their amino groups, PAMAM dendrimers are weak polyelectrolytes. Lowering the pH results in an increasing protonation of the amino groups which is monitored via the proton chemical shifts of the adjacent CH2 groups. The effective ch...
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Polyglycerol, porphyrin-cored dendrimers were synthesized by the click reaction of azide-cored polyglycerol dendrons and octaazidoporphyrin 19. The dendrons were synthesized divergently starting with TBDPS protected allyl alcohol 2. Two, three and four cycles of dihydroxylation-allyl etherification gave dendrons [G-2.5] 6, [G-3.5] 8, [G-4.5] 11, with four, eight, and sixteen alkene groups, resp...
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Nanoparticles (NPs) have gained huge interest in the medical field, in particular for drug delivery purposes. However, binding of proteins often leads to fast NP uptake and rapid clearance, thereby hampering medical applications. Thus, it is essential to determine and control the bio-nano interface. This study investigated the serum protein interactions of dendritic polyglycerols (dPGs), which ...
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ژورنال
عنوان ژورنال: Macromolecules
سال: 2017
ISSN: 0024-9297,1520-5835
DOI: 10.1021/acs.macromol.7b00742